Resveratrol-Loaded Attalea funifera Oil Organogel Nanoparticles: A Potential Nanocarrier against A375 Human Melanoma Cells
نویسندگان
چکیده
This study aimed to evaluate Attalea funifera seed oil with or without resveratrol entrapped in organogel nanoparticles vitro against A375 human melanoma tumor cells. Organogel (SON) the (RSON) formed functional that showed a particle size <100 nm, polydispersity index <0.3, negative zeta potential, and maintenance of electrical conductivity. The entrapment efficiency RSON was 99 ± 1%. SON no cytotoxicity non-tumor cells Resveratrol at 50 μg/mL cytotoxic for cells, 25 μg/mL. decrease Thus, is potential new platform delivery selective activity treatment melanoma.
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2023
ISSN: ['1661-6596', '1422-0067']
DOI: https://doi.org/10.3390/ijms241512112